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Streptokinase for Acute Ischemic Stroke with Relationship to Time of Administration
JAMA 276:961-966, 9951996., Donnan,G.A.,et al, 1996
See this aricle in Pubmed

Article Abstract
The administration of streptokinase within 4 hours of acute ischemic stroke increased morbidity and mortality at 3 months.While treatment within 3 hours of stroke was safer and associated with significantly better outcomes than later treatment,it showed no significant benefit over placebo.The timing of thrombolytic therapy for acute stroke is critical.
 
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cerebrovascular accident
cerebrovascular accident,acute management of
cerebrovascular accident,thrombolytic agents in treatment
emergencies,medical
emergencies,neurologic
fibrinolytic agents
fibrinolytic agents,complications
placebo
streptokinase
treatment of neurologic disorder

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